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Melasma is driven by ongoing hormonal triggers (estrogen, progesterone) and cumulative UV exposure that continuously stimulate melanocytes these triggers do not stop because a treatment course ends
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In contrast, IGF-1 LR3's extended half-life allows for a more prolonged anabolic effect, making it a preferred choice for those seeking significant results in muscle development
Studies should include sex, age, and relevant comorbidities whenever possible because diabetes, hypertension, obesity, and aging may modify treatment response [1, 5, 9]
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