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The real magic happens at the cellular level

Linear mixed-effect model analysis revealed a significant main effect of time ( F 1,74 = 197.93, P 0.5, blinding was considered successful (Supplementary Table 3)

Chinese Journal of Endocrinology and Metabolism, 2022, 38(8):700-748

Although its functionality is not compromised, this imposes a certain level of simplification of cell death pathways in mature erythrocytes as compared with the nucleated cells