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Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis was published in The BMJ in January 2024

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Semaglutide works by shrinking fat cells, but it simultaneously multiplies the number of fat cells you have so it is probable that you will need to use the medication as a life-long therapy to prevent weight gain in the future unless you have a significant lifestyle change

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