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So injecting beyond a certain point may cause your cells to fight off the excess B12 so hard that it might reduce the amount of active cellular B12 - probably not to dangerous levels, but possibly sufficient to trigger some symptoms

Lifestyle factorslike diet, exercise routine, sleep quality, and stress levelsplay a significant role in whether AOD-9604 delivers noticeable changes in body composition

A vitamin B-12 supplement of 500 g/d for eight weeks does not normalize urinary methylmalonic acid or other biomarkers of vitamin B-12 status in elderly people with moderately poor vitamin B-12 status

But it is still unclear whether B12 injections can promote weight loss in humans