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At the receptor level, MK-677 binds the growth hormone secretagogue receptor 1a (GHS-R1a) on somatotroph cells of the anterior pituitary and on hypothalamic neurons, mimicking the orexigenic peptide ghrelin
It induces lipolysis, actively breaking down stored fat into usable energy
So, when blood sugar levels are elevated particularly after eating GLP-1 agonists spur insulin production leading to lower blood sugar levels, which is ultimately beneficial for controlling type 2 diabetes
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