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PLoS One 17 , e0274735
GLP-1 improves microvascular blood flow by increasing endothelial function, causing vasodilation, and reducing systemic vascular resistance
Many of these older drugs had been grandfathered in when the new drug approval process was established in the 1960s, so they had never undergone clinical studies to secure FDA approval
The body can also experience skin laxity, stubborn fat pockets, and diminished tone
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