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Early observations came from gastric studies, then attention spread to soft tissue under mechanical stress
Treg cells actively uptake lactate through MCT1, which facilitates the NFAT1 translocation into the nucleus, thereby promoting the expression of PD-1 and contributing to tumor immune inhibition [298]
Speranza L, Di Porzio U, Viggiano D et al (2021) Dopamine: the neuromodulator of long-term synaptic plasticity
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