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The short answer is that tirzepatide (the active ingredient in Mounjaro and Zepbound) appears to be slightly more effective than semaglutide (the active ingredient in Wegovy and Ozempic) in studies both for weight loss and diabetes
But as labs, symptoms, and dose changes accumulate, those methods fragment context and make clinic visits longer and more stressful
Thyroid C-cell effects: Preclinical studies with GLP-1 receptor agonists have identified thyroid C-cell changes in rodents
doi: 10.1007/S11154-014-9289-5 27 KalinderiKPapaliagkasVFidaniL
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