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On the other hand, unlike in BPC 157-rats (BPC 157 given alone), PT-values remained prolonged (warfarin-rats), here, after heparin, or warfarin, BPC 157+L-arginine-rats, BPC 157+L-NAME-rats, BPC 157+L-arginine+L-NAME-rats exhibited no reduced bleeding time and no effect on prolonged PT-, APTT-, TT- values (heparin-rats)

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Hierarchy of Evidence: Level D (Pre-clinical animal models)

In the Phase 2 dose-finding trial, men and women receiving cagrilintide 4.5 mg achieved mean weight loss of 10.8% over 26 weeks