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Tirzepatide is presently being examined in a clinical trial (NCT04847557) for patients with moderate HF (NYHA class II-IV) with HFpEF [54]

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TRIUMPH-1 TRIUMPH-1, a randomized, placebo-controlled phase 3 study, assessed the safety and efficacy of weekly retatrutide on weight reduction and health in adults with obesity or overweight, including subsets of participants with obstructive sleep apnea (OSA) or knee osteoarthritis (OA)