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The EMA website says the shortage of Novos Wegovy has been resolved but Lillys Trulicity and Novos Saxenda continue to be in shortage.
In particular, increased plasma insulin concentrations stimulate the gonadotropin releasing hormone (GnRH) pulsatility and potentiate the LH-dependent effect on the ovarian theca cells, leading to the enhanced synthesis of androgens and to the arrest of pre-antral follicle development [13]
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