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In sum, much current research is aimed at understanding the endogenous GLP-1 system in the brain, particularly how GLP-1R agonists gain access to certain regions of the brain and their effects once they are in the brain, but the complexity of GLP-1 pathways has so far kept scientists from developing a complete understanding of the system.
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Across all demographic subgroups, GLP-1 RA users consistently exhibited an elevated risk of psychiatric diseases
Furthermore, GCs also promote lipogenesis in the liver, which leads to an increase in the secretion of very low density lipoproteins (VLDL)
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