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Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-B in mice

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Its mechanisms of action include: Stimulating insulin secretion from pancreatic -cells in a glucose-dependent manner Suppressing glucagon release , reducing hepatic glucose production Slowing gastric emptying , which reduces postprandial glucose spikes Promoting satiety , leading to reduced caloric intake and potential weight loss Semaglutide has a half-life of approximately 1 week , allowing for once-weekly dosing , which improves adherence compared to daily injections