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It is likely that losses of soluble sugars required for aerobic respiration would limit NADH production from glycolysis and the tricarboxylic acid cycle

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Consistently, the GPx3 levels were reported to be down-regulated in aggressive inflammatory breast cancer (IBC) carcinoma tissues compared to non-IBC tissues, and this down-regulation was associated with hypermethylation of the GPx3 promoter [103]