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The safety evidence is solid
MGF (Mechano Growth Factor) is the unique E-domain peptide from the IGF-1Ec splice variant, a naturally occurring repair signal expressed locally in response to mechanical tissue damage
E.Van't VeerP.et al (2013)
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Under inflammasome related pyroptotic stress, caspase-1 and gasdermin D promote mtDNA escape into the cytosol, then drive intraluminal vesicle formation that enables mtDNA loading into intraluminal vesicles (ILVs) and release via exosomes
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