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Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response
Important safety considerations include gastrointestinal side effects (nausea, vomiting, diarrhoea), risk of gallbladder disease, pancreatitis, dehydration leading to acute kidney injury, and worsening diabetic retinopathy with rapid glycaemic improvement
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And shell be watching to see how the legal fight influences public trust and the market for such drugs while raising larger questions about what level of drug risk warnings are deemed sufficient
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