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For isolated knee osteoarthritis or tendinopathy without GI involvement, PRP carries stronger evidence justification despite higher cost
[6] Propionate specifically has been shown to stimulate GLP-1 and PYY (another satiety hormone) release via FFAR2 in rodent and human colonic tissue
Once symptoms improve, a lower dose might be used
Rayyan software ( 2.4 Study selection, eligibility criteria, and data extraction Reviewers underwent training at each step of the process, and a pilot screening was conducted to ensure consistency in applying the eligibility criteria
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