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Approaches to improve macromolecule and nanoparticle accumulation in the tumor microenvironment by the enhanced permeability and retention effect
The mutation of GIPR Glu 354 to Gln increases GIP affinity, enhances the agonist residence time by 25%, increases cAMP activity, and facilitates the rate of internalization by 2.12.3-fold
doi: 10.1007/s13399-024-05308-8 137
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