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Oxidation of dopamine and consequent quinone modification contribute to the vulnerability of dopaminergic neurons ( Mitochondrial Dysfunction Neuronal ATP formation depends on mitochondrial aerobic respiration, which normally produces hydrogen peroxide and superoxide radicals as byproducts during mitochondrial oxidative phosphorylation ( c , and eventually triggering apoptosis ( Neuroinflammation In response to neural tissue injury or toxic insult, microglial cells undergo activation as a self-defensive mechanism

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The search strategy was developed using keywords and Boolean operators such as rumen-protected methionine, methionine supplementation AND dairy cows, and methionine supplementation AND beef cattle. After retrieval, duplicate records, in vitro studies, literature reviews, and meta-analyses were removed