1 Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a growing epidemic associated with metabolic disease ( Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), including liraglutide, exenatide, semaglutide, beinaglutide, and dulaglutide, are commonly used in clinical practice to manage blood sugar and body weight
If you lose 20 pounds, but 8 of them are lean muscle tissue, you have arguably worsened your metabolic health, not improved it
Research indicates that the blood pressure-lowering effect might be even more significant in patients with established hypertension, though more studies are needed to confirm this hypothesis
Besides, not all elder T2DM patients have cardiovascular risks, and there are explicit evidences that SGLT-2 inhibitors can increase the risks of urinary tract infection and genital infection