Simone Gabriele, director, Ipsos Global Healthcare Monitors Immunology Drug: Ianalumab Company: Novartis Indication: Sjgrens disease Stage: Phase III Background: Positioned as a potential first-in-class targeted therapy for Sjgrens disease (SjD), ianalumab made a splash in 2025 with positive Phase III topline results in SjD and blood disorder immune thrombocytopenia
Noticeable weight loss typically takes several weeks and depends on consistently following a reduced-calorie, low-fat diet and exercise program alongside the medication
This shifts fat storage patterns back toward a healthier distribution, improves sleep, stabilizes mood, and, critically, restores GLP-1 receptor sensitivity in the brain
In this section, well explore why a person might need both medications, what types of health problems may require them, and how to manage these medications together