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Arm muscle area (AMA) did not change significantly in the L-carnitine group but decreased significantly in the control group

The liver produces IGF-1 in response to growth hormone stimulation

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4 Translational applications and innovative delivery platforms in preclinical models 4.1 Biomimetic and cell membrane-coated nanoparticles The clinical translation of nanomedicine platforms for osteosarcoma immunotherapy requires not only potent antitumor activity but also favorable biocompatibility, targeted delivery, and the ability to overcome biological barriers