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The authors also found that the glycine-amidated conjugates of the BAs and deoxycholic acid (DCA) increased more than the taurine conjugates, resulting in a more hydrophobic pool of BAs, which as noted above are more cytotoxic (Deo and Bandiera 2008)
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Left unmodified, most therapeutic peptides would have half-lives measured in minutes, which is exactly what you see with sermorelin and tesamorelin, both close analogs of endogenous GHRH
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