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Description

In WT and obese animals, AOD9604 reduces fat mass, increases 3-AR expression, enhances lipolysis, and stimulates energy expenditure and fat oxidation

The mechanics (add water, aim at glass, swirl, refrigerate) do not change

For observational studies (cohort and case-control), the NewcastleOttawa Scale (NOS) ( Risk of bias was interpreted as follows: i) Low risk: All criteria met or no more than one rated as unclear

The key pharmacological difference is duration of action: the trans-3-hexenoic acid modification extends the effective half-life, producing a more sustained and reproducible GH pulse