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V., Lee, Y
When GLP-1 binds to these receptors, it can shift macrophages from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype, inhibit the production of pro-inflammatory cytokines like TNF-, IL-1, and IL-6, increase anti-inflammatory adiponectin, and inhibit NF-B, a key regulator of pro-inflammatory gene expression
Novo Nordisk Canada announced it will reduce the price of brand-name Ozempic for eligible Canadians without public or private drug coverage, with the discount taking effect Friday and explicitly framed as "aligning their medication costs with generic alternatives"
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