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Neuropharmacology 149, 124132
Without a modest calorie deficit, adequate protein, and regular movement, the fragment has far less to work with, because it influences how the body handles fat rather than forcing weight off on its own
However, in chronic liver diseases, LSEC may lose their unique fenestration features, becoming capillarized, thus disrupting their role in maintaining the quiescent state of HSCs and contributing to liver fibrosis (Poisson et al., 2017)
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