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356 In DNA damageinduced conditions, frequent inactivation of the SLFN11 gene in tumor cells leads to the loss of its tRNAse activity, causing ribosome stalling and inhibition of protein translation
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In fact, studies show that as many as 40% of ALL thyroid patients have this deficiency (1)
2.3 Information sources and search strategy Three databases (PubMed, Embase, and Scopus) were searched up to 15 July 2024
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