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Glutathione is involved in detoxification, it binds to toxins, such as heavy metals, solvents, and pesticides, and transforms them into a form that can be excreted in urine or bile

Journal of Orthopaedic Research , 1999

These insights have led to therapeutic strategies targeting hypoxia and tumor metabolism, including HIF-2 inhibitors (e.g., belzutifan), hypoxia-activated prodrugs, anti-angiogenic agents, glycolysis and glutaminase inhibitors, lactate transport blockers, CAIX inhibitors, and immunometabolic modulators aimed at reversing hypoxia-induced immune suppression [ Table 1 ]

These treatment outcomes would benefit patients suffering from AD and other neurodegenerative diseases