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They are not recommended for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Describing herself as largely 'the lab rat' when she joined the diabetes team, Knudsen remembers she spent 'the first year in a cold room with three technicians to screen hundreds of thousands of compounds to see if they could wedge into the GLP-1 receptor and other targets of interest just snugly enough to stimulate insulin secretion.' To help speed up the screening process, Knudsen devised a method to test 96 candidates in one go instead of just one
These factors make it harder to generalize the findings and fully evaluate the long-term effectiveness and safety of these treatments
Used for reducing symptoms of peripheral neuropathy and diabetic nerve pain
