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side effects Somnolence (long half-life may increase risk of prolonged sedation)
A decrease in body weight, blood pressure, HbA1c, fasting insulin, insulin resistance, plasma glucagon, total cholesterol, lipids, FPG, SMBG, cardiovascular death, nonfatal stroke, and myocardial infarction are observed with the use of semaglutide in monotherapy or in combination with other antidiabetic drugs
Research from the STEP-1 clinical trial found that approximately 45% of total weight lost on semaglutide came from lean mass, not fat
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