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The ferroptosis inhibitors evaluated to date mainly play a role by inhibiting lipid peroxidation, upregulating GPX4 expression, and maintaining iron homeostasis
GLP-1 drugs help people lose weight, which is important because the risks from obesity account for 40% of all cancer diagnoses in the U.S., impacting prognosis and survival
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5 Future directions The potential of GLP-1RAs as dual-action therapies, targeting both metabolic dysfunction and immune dysregulation, makes them particularly compelling candidates for early PsA, where intervention may alter disease trajectory
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