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A significant focus was on developing inhibitors of insulin-regulated aminopeptidase (IRAP), a protein identified as the AT4 receptor, with the goal of enhancing metabolic stability and BBB permeability
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Additionally, other studies have shown that collagen peptides significantly improved UV-induced photoaging in mouse skin models by activating the TGF-/Smad pathways, promoting the synthesis of hyaluronic acid and collagen, and downregulating MMPs [36, 37]
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