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However, patients with higher BMIs may need longer at certain phases before they notice meaningful appetite suppression, which is a normal variation and not a sign the medication is not working.
Considering it's been found to help increase satiety, balance energy levels and interact with the gut microbiome, studies also have shown that higher GLP-1 levels are associated with reduced food intake and improved metabolic markers as well
Over the year after withdrawal, participants regained about two thirds of prior weight loss, and improvements in blood pressure, lipids, and glycaemic markers tended to revert toward baseline
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