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The process used is solid-phase peptide synthesis (SPPS), in which amino acids are coupled sequentially onto a resin bead, one at a time, in exact sequence
Patients who notice worsening digestive symptoms should talk to their doctor, as they may need an adjustment in dosage or a change in medication
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N Engl J Med 370(15):13831392 Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ et al (2003) Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial
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