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56 This may require blood glucose targets to be higher (i.e., 90-150 mg/dL) temporarily depending on the individual patient to help avoid severe hypoglycemia
Furthermore, we found that AdOx treatment reduced the protein level of wild-type GLUD1, but had no effect on the methylation-deficient R76K mutant (Fig
Even a recent 2026 review concludes the same thing that GHK-Cu appears safe but the evidence is largely preclinical and comprehensive human RCTs are lacking (Wojcieszuk et al., 2026)
Referral to a registered dietitian is appropriate for patients with significant fatigue, rapid weight loss (more than 1-2% body weight per week), or concerns about nutritional adequacy
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