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Although clinical differences between selenium treatment and placebo could not be observed in any subgroup, further studies may build on these findings to define a specific responder phenotype that may be susceptible to anti-inflammatory treatment strategies with high-dose selenium

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The SH bond is much weaker than the OH bond as reflected in their respective bond dissociation energies (BDE)

Glutathione also acts as an anti-inflammatory, which can help ease symptoms associated with autoimmune diseases where inflammation is a key factor