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Second, several experiments whether they involve slices of brain tissue, animals, and even human volunteers have strongly suggested that GLP-1 drugs specifically act on our dopamine cycles and affect neural activity in the hypothalamus, the appetite-controlling region of the brain
The SURMOUNT trial program provides extensive data on what tirzepatide achieves without any additional weight loss medication: 5 mg dose: 15.0% average weight loss at 72 weeks 10 mg dose: 19.5% average weight loss at 72 weeks 15 mg dose: 20.9% average weight loss at 72 weeks At 15 mg, 56.1% of participants lost at least 20% of body weight At 15 mg, 38.7% of participants lost at least 25% of body weight These numbers are remarkable
Absorption rates vary slightly by site
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