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The scenario where adding phentermine makes the strongest case is this: a patient on maximum tirzepatide dosing for at least 6 months, with a documented weight loss plateau lasting 8 or more weeks, who has optimized diet, exercise, sleep, and stress management, and whose provider has ruled out medical causes for the plateau (thyroid dysfunction, medication interactions, fluid retention)

We recently learned of an elite drug rehab center this is using GLP-1 drugs as the primary method to treat addiction

and Burastero, S.E., 2015

Except now his testosterone levels were at 10 ng/dL, so his doctor put him on testosterone replacement therapy (TRT)