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Function of ABCG2 The export process of ABCG2 is ATP-dependent and unsaturated at the physiological concentration of UA, indicating that ABCG2 has high-capacity urate transport activity (Matsuo et al., 2009)

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Although high-quality clinical studies directly reporting combination therapies as ineffective or harmful are uncommon, inconsistencies persist in the existing evidence

Liver Detoxification Cofactor The liver uses glutathione in Phase II detoxification to conjugate and neutralize toxins, heavy metals, and metabolic byproducts before they are eliminated