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More recently, various mutations have been discovered that influence the central enzymes of the methylation cycle the MTHFR mutation has already been discussed in this context

Flavonoids are important because they act as free-radical scavengers and antioxidants, exhibiting anti-mutagenic, anti-inflammatory, and antiviral effects[and] are able to reduce plasma levels of low-density lipoproteins, inhibit platelet aggregation, and reduce cell proliferation. (Salehi, 2019)