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Lets break down every method people try and be honest about what actually works
Pentostatin also can inhibit RNA synthesis, cause DNA strand breaks, disrupt ATP-dependent cellular processes, and inhibit adenosylhomocysteinase (S-adenosylhomocysteine hydrolase), all of which also may contribute to the drug's lymphocytotoxic effects
Similarly, in the analysis that included both controlled and non-controlled studies, we built several linear regression models to assess whether the heterogeneity in the effect measure could be explained by differences in intensity, volume and type of exercise among study arms
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