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Safety Considerations and Side Effects A lot of attention needs to be given to IGF-1 LR3 as it is a powerful molecule and has more warnings associated with it than most other peptides: Hypoglycemia risk Because IGF-1 is similar in structure to insulin and can bind to the insulin receptor when present in high concentrations, use of IGF-1 LR3 has been implicated in users experiencing low blood sugar

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[126] demonstrated in a drug clinical study in 2018 that GLP-/GIP dual agonists could significantly reduce TG and TC levels in patients compared with placebo

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