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GSH deficiency results in the activation of von Willebrand Factor (Ibrahim et al., 2004) and in the accumulation of ROS, which affect clotting and platelet activation, impair endothelial function, and predispose to the risk of thrombotic events (Violi et al., 2017): notably, hypercoagulation is a prominent life-threatening complication in COVID-19 patients (Giardini et al., 2020)
During ovarian aging, reduced localization and levels of peroxisomal markers (e.g., PEX14) may reflect impaired peroxisomal homeostasis [298]
Glutathione Inhibits tyrosinase activity: The primary mechanism by which glutathione effectively reduces dark spots, patches, and uneven skin tone is the inhibition of tyrosinase activity
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