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Curcumin significantly up-regulated the expression of Slit-2 in Ishikawa, Hec-1B and primary endometrial cancer cells, while it down-regulated the expression of SDF-1 and CXCR4, which in turn, suppressed the expression of MMP 2 and 9, thus attenuating the migration of endometrial cancer cells
For patients with significant weight to lose, staying on treatment longer consistently produces better outcomes
Phase 3 readouts have since pushed even higher in some populations
The treatment includes 1000 mg NAD and a minimum of 500 milligrams of Normal Saline
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