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Ebselen protection against hydrogen peroxide-induced cytotoxicity and DNA damage in HL-60 cells

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Thiol/disulfide is a critical component of the antioxidant defense system and is necessary for maintaining the intracellular redox balance and for the diagnosis and prognostic assessment of potentially lethal diseases (Chatterjee and Hausinger, 2022)

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5.0 Pharmacological properties 5.1 Mechanism of action Glutathione is an extremely important cell protectant which directly quenches reactive hydroxyl free radicals, other oxygen-centered free radicals, and radical centers on DNA and other biomolecules

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