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Validation of differentially expressed proteins or biomarkers by peptide intensity and ELISA assay quantification To validate the differentially expressed proteins identified in plasma samples across the three groups, we selected CST3, GAPDH, PCSK9, C1QA, CPB2, and PRDX6 based on significant fold changes and pathway enrichment scores

Although, therapeutic (as opposed to prophylactic) relevance has yet to been assessed, our discovery highlights the potential of BHB and a ketogenic diet as a broadly applicable treatment to enhance functional T cell responses in nutrient-deprived environments, which are commonly observed in the context of infections but also tumour growth

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