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Desire is experienced if the balance of excitatory and inhibitory factors is tipped toward excitatory
When gastric emptying is slow and the LES is under additional functional pressure, heartburn becomes more likely even with smaller meal volumes
comorbidities (essential hypertension, heart failure, ischemic heart disease, chronic kidney disease [CKD], cerebrovascular disease, overweight/obesity, dyslipidemia)
They're marketing funnels, not objective comparisons
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