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A study from 2011 took subjects with chronic non specific low back pain (meaning there was no specific reason for their back pain) and gave them three injections of Vitamin B12 per week over a two week period
Aim for a modest caloric deficit of 300-500 calories below maintenance, with protein intake around 0.8-1 gram per pound of body weight
Patients with early hereditary optic nerve atrophy, cyanocobalmin hypersensitivity, and those who are pregnant
Seven additional Phase 3 readouts are expected through the remainder of the year, covering applications in type 2 diabetes, obstructive sleep apnea, chronic low back pain, cardiovascular outcomes, and metabolic liver disease
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