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Titration: Follow the dosage escalation schedule, titrating every 30 days to achieve the maintenance dosage
Some companies are investigating microbe-based ingredients to boost insulin sensitivity, while others are turning to plant-based sweeteners like stevia and monk fruit
For islet perifusion, 75 islets were handpicked and loaded into 0.275 mL chambers containing KRPH (140 mM NaCl, 4.7 mM KCl, 1.5 mM CaCl 2 , 1 mM NaH 2 PO 4 , 1 mM MgSO 4 , 5 mM HEPES, 2 mM NaHCO 3 , 1% fatty acid-free BSA) in 2.7 mM glucose
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