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However, even in large real world cohorts of patients with T1D on GLP-1RA, low rates of hypoglycemia were observed ( ADJUNCT ONE and TWO trials, the 2 largest studies with GLP-1RA in T1D, reported increased rates of hypoglycemia

(2014) ran a phase 2, randomised, double-blind, placebo-controlled proof-of-concept study (NCT00672074, sponsored by Helsinn Therapeutics (U.S.), Inc.) in bowel resection patients: 117 patients enrolled, of whom 114 composed the safety and modified intent-to-treat populations, receiving intravenous infusions of 0.03 mg/kg twice daily on postoperative day 1 to 7 or hospital discharge

Kolkhof P, Brfacker L

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